Michael Caplan, MD is no stranger to the University of Michigan Department of Pathology.  This is actually his fourth time joining the Department! After completing a BS in Criminalistics at Michigan State University and an MD from the University of Connecticut School of Medicine, Caplan joined the Department for the first time as an AP/CP Resident from 1987-1992.

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Technological advances have made telepathology a reality for many pathologists, allowing challenging case consultations regardless of where the expert may be located.  Recently, Dr. Liron Pantanowitz, Director of Anatomic Pathology, presented a keynote address entitled, "Telepathology: Still the #1 application of digital pathology" at the 7^th Digital Pathology & AI Congress: Europe, December 1, 2020.

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While in medical school, Dr. Myra Kahn discovered her love for gross pathology during a pathology rotation. This led her to a residency in Anatomic Pathology at the University of Chicago from 2014-2018.  As a resident, Forensic Pathology “[put] together my interest for gross pathology along with autopsy,“ shared Khan. She also discovered her love for breast pathology [...]

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A new study by the University of Michigan's Rogel Cancer Center analyzed patients with cancer and the factors that cause the cancer to spread to the liver, leading to worse outcomes. 

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Clinical trials underway are testing whether drugs that target the androgen receptor – successful in controlling prostate cancer – could also work against the coronavirus. wo proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, MD, PhD. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers [...]

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Recently, Department of Pathology faculty member Dr. Laura Lamps appeared on the December 3 episode of the PathPod Pocast's Beyond the Scope. In the episode, Dr. Lamps discusses a varierty of topics including her role as the Director of Gastrointestinal Pathology at Michigan Medicine, her involvement in United States and Canadian Academy of Pathology (USCAP), personal hobbies and her experience working in medicine overall [...]

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Congratulations to Suzanne Butch for winning the American Association of Blood Banks’s 2020 President’s Award.  This award was in recognition of her “extraordinary work with the ISBT Working Party on Information Technology and [her] leadership in moving the ISBT 128 labeling program forward.” [...]

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A new study led by Drs. Jolanta Grembecka and Tomasz Cierpicki of the Department of Pathology was just published in Blood's American Society of Hematology. The research focuses on combinatorial treatment with menin and FLT3 and how inhibitors induce complete remission in acute myeloid leukemia (AML) with activating FLT3 mutations [...]

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Congratulations to Dr. Thomas Giordano and the entire Cancer Genome Atlas Project team for winning the American Association of Cancer Research's 2020 Team Science Award [...]

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New research by the Department of Pathology was recently published in Modern Pathology. The study, led by Drs. Aaron Udager, Noah Brown, Bryan Betz, Jonathan McHugh and Scott Tomlins, focuses on how TP53 mutations and CDKN2A mutations and deletions are highly recurrent molecular alterations within malignant progression of sinonasal papilomas [...]

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Congratulations to Dr. Celina Kleer who was awarded the American Society for Investigative Pathology (ASIP)'s 2020 Outstanding Investigator Award. Dr. Kleer receives the award for her demonstrated excellence in research in experimental pathology [...]

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Congratulations to Usha Kota, BS, MT(ASCP) on her retirement following 32 years in Pathology! Usha began in Pathology in 1988 in the blood bank, moving to flow cytometry in 1989. In 1990, she was promoted to senior technologist, then flow cytometry supervisor in 1994.  In 2005, she was promoted to laboratory supervisor of Hematology [...]

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Research by the Department of Pathology's Drs. Richard Miller and Joseph Endicott was just published in the Journal of Cell Biology. The study focuses on the inhibition of class I PI3K and how it enhances chaperone-mediated autophagy (CMA) [...]

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Congratulations to Dr. Jeffrey Myers, who was recently selected by Michigan Medicine for the 2020 Jack Billi Award for Inspiring Quality Improvement. Dr. Myers was selected for his exemplifying behaviors of an effective improvement leader and for using LEAN design principles and tools in his daily work [...]

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Experts from the Department of Pathology's Phlebotomy Team were featured on Michigan Medicine's "The Wrap" podcast. The podcast focuses on the department's Poke Plan Program at C.S. Mott Children's Hospital, an initiative that helps to alleviate pain and fear among children during the blood draw process [...]

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Diarrhea can be the unfortunate but short-lived side effect of bad takeout food, yet it is also a leading cause of death in children under five globally. Scientists continue to investigate how illness-causing bacteria gain a foothold within the digestive tract when they are usually held in check by the protective bacteria collectively known as the gut microbiome [...]

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Congratulations to Don Giacherio, PhD, who retired July 31, 2020, following 38 years of service in the University of Michigan Department of Pathology. Giacherio completed his PhD at the University of Illinois in 1980, followed by a 2-year postdoctoral fellowship at Mayo Clinic. In 1982, Giacherio joined the University of Michigan Department of Pathology as an Instructor in Pathology [...]

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New research from the Department of Pathology and Dr. Alexandra Hristov was just published in the Journal of Cutaneous Pathology. The study focuses on the kappa and lambda immunohistochemistry in situ hybridization of atypical cutaneous lymphoid infiltrates. 

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Kathy Davis, IT Administrative Director in Pathology Informatics, retires after more than 40 years of service to the Department of Pathology. Over her career, she has contributed to lab information system software development efforts that have impacted the history of pathology informatics, both at Michigan and nationally.

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In a recently published Nature Reviews-Nephrology review article, “Digital pathology and computational image analysis in nephropathology,” Dr. Ulysses G. J. Balis discussed how the emergence of digital pathology — an image-based environment for the acquisition, management, and interpretation of pathology information supported by computational techniques for data extraction and analysis — is changing the pathology ecosystem [...]

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The University of Michigan will begin a Sampling and Testing Program of asymptomatic students, faculty and staff for the virus that causes COVID-19 on September 7.

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In a broadly collaborative effort, Pathology faculty Drs. Carl Schmidt, Jeffrey Myers, Kristine Konopka, Paul Lephart, and Teresa Nguyen joined Michigan Medicine faculty from the departments of Epidemiology, Internal Medicine, Microbiology and Immunology, Mathematics and Complex Systems, and the School of Public Health in a study published in Clinical Infectious Diseases entitled “SARS-CoV-2 surveillance in decedents in a large, urban medical examiner’s office.”

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Structural biology techniques helped researchers target the nuclear receptor-binding SET domain family, whose malfunction is associated with several types of cancer.

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"Patient advocacy and engagement is essential to provide high quality care.  Your dedication to empower other patients through education and awareness has made big contributions to the life-changing impact of patient-pathology interactions.”  So begins the award letter to Michele Mitchell from the American Society for Clinical Pathology (ASCP), who is awarding Michele the ASCP Patient Champion Award for 2020... 

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In a new study, Chan Chung et al. from the Venneti laboratory have discovered a “catch 22”-like phenomena, where epigenetic and metabolic pathways feed one another, in a childhood brain tumor called Diffuse Intrinsic Pontine Gliomas (DIPG) [...]

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When people think about forensic pathology, images of crime shows where an investigator sets out to determine a murder victim’s cause of death often come to mind. However, it’s important to acknowledge the crucial role this field actually plays in our collective response to death, especially as the COVID-19 pandemic continues to unravel...

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Dr. Vincent Laufer was recently awarded the 2020 William Boyd Medal for the Outstanding Student in Pathology. The award is given to a medical student who demonstrates outstanding expertise in all aspects of their pathology education [...]

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Dr. Celina Kleer named 2019 AACR Outstanding Investigator in Breast Cancer Research

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Dr. Aaron Udager recently appeared on Michigan Medicine's 3P's of Cancer: Prevention, Preparedness, Progress podcast

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Pathology Welcomes 8 New Residents

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New research related to H3K27M-mutant diffuse midline glioma with extensive intratumoral microthrombi in young adults with COVID-19 from the Department of Pathology was just published in Acta Neurologica. [...]

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Please welcome Dr. Pantanowitz to the Department.

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The Department of Pathology has a long history of exceptional fellowship directors and this tradition continues as we welcome five new Fellowship Directors for this academic year.

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Research from Dr. Analisa Difeo was just published in Nature Communications. The study focuses on miR-181a and how it initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling [...]

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On Friday, June 19, the Department of Pathology hosted an Equality Walk at NCRC `in observance of the Juneteenth holiday. Here, members from all areas of the department gathered to show their support against racial discrimination and for the Black Lives Matter movement.

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Graduating Class of Residents.

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Graduating Class of Fellows and Clinical Lecturers.

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The publication takes an in-depth examination of diffuse alveolar damage (DAD) caused by COVID-19 and how it is morphologically indistinguishable from other causes of DAD.

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Dr. Jeffrey Myers discusses the importance of frontline workers and their caring of patients - alive or deceased - during the COVID-19 pandemic.

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The research was just published in Modern Pathology and highlights the importance of next-generation sequencing within oncogenic roles for P53 and JAK/STAT signaling in microcystic adnexal carcinomas.

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Congratulations to Thomas Annesley, PhD, on winning the 2020 IFCC Award for Distinguished Contributions in Education.

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Peter Ouillette, MT (ASCP) shares his experience working as the Department's Digital Pathology Operations Manager.

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The protein Argonaute 2 was found to be critical to the progression from benign lesions into pancreatic cancer, suggesting a therapeutic opportunity.

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The research, which focuses on invasive squamous cell carcinomas and the precursor lesions that demonstrate concordic genomic complexity in driver genes, was just published in Modern Pathology.

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Serology testing for SARS-CoV-2 is now available for ordering on appropriate patients at Michigan Medicine. A separate process for testing and screening of health care workers and Michigan Medicine affiliates will be communicated in the coming weeks.

The serology test detects specific antibodies generated as part of the immune response to SARS-COV-2 infection. Our current test methods detect  [...]

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The research was just published in Histopathology and features prominent contributions from our faculty.

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Selections will be chosen in a virtual ceremony on June 20.

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The Department of Pathology 2019 Annual Report is now available online. Our department continues to show outstanding performance and growth and the past year was another example of why our department is one of the best in the world.

In the report, you will read about [...]

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Dr. Farkash recently sat down with the podcast team to discuss renal pathology during the COVID-19 pandemic.

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The study pertains to the molecular characterization of uterine and ovarian tumors and their relationships to epithelial and germ cell features by somatic derivation.

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