The department of Pathology supports a robust research program including over 100 research faculty in over 40 laboratories, with 12 endowed professorships. Broad areas of research interests encompass basic, translational and clinical sciences, and utilize state of the art multi-disciplinary approaches investigating the pathobiology of human disease. Research programs in U-M Pathology encompass a wide range of topics in the areas of Aging, Allergy, Cancer Biology, Development & DNA repair, Inflammation and Immunology, Mucosal Inflammation and Epithelial Pathobiology, Neurobiology/Pathology and Bioinformatics. Research strengths are further complemented by innovative clinical and translational research programs in Anatomic and Clinical Pathology.
Pathology research at U-M is supported by funding from the NIH, NSF, DOD, private foundations and pharmaceutical industry and ranks in the top ten nationally among Pathology Departments. Our recruitment efforts as well as recent funding successes have positioned U-M Pathology as a leading research destination in Pathology nationally.
New research related to H3K27M-mutant diffuse midline glioma with extensive intratumoral microthrombi in young adults with COVID-19 from the Department of Pathology was just published in Acta Neurologica. [...]
Research from Dr. Analisa Difeo was just published in Nature Communications. The study focuses on miR-181a and how it initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling [...]
The publication takes an in-depth examination of diffuse alveolar damage (DAD) caused by COVID-19 and how it is morphologically indistinguishable from other causes of DAD.
The research was just published in Modern Pathology and highlights the importance of next-generation sequencing within oncogenic roles for P53 and JAK/STAT signaling in microcystic adnexal carcinomas.