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Biomarker Could Help Identify Difficult-to-Diagnose Kidney Cancer Subtype

MiTF renal cell carcinoma can masquerade as other subtypes and may not respond as well to front-line therapies.

April 14 2021

Prognostic Subgroups of Merkel Cell Carcinoma Defined

A collaboration between the Department of Pathology and the Department of Dermatology examined biomarkers of outcomes in 346 cases of Merkel cell carcinoma (MCC), an aggressive type of skin cancer. The study was published in the recent edition of Clinical Cancer Research [...]

February 9 2021

Research from Dr. Udager Published in European Urology

A new publication, generated by Department of Pathology faculty members Drs. Aaron Udager and Scott Tomlins was successfully published in European Urology. The research highlights a longitudinal cohort study centered around the serial molecular profiling of low-grade prostate cancer in order to better assess tumor upgrading [...]

February 1 2021

Study Explains Why Patients with Cancer Spread to the Liver Have Worse Outcomes

A new study by the University of Michigan's Rogel Cancer Center analyzed patients with cancer and the factors that cause the cancer to spread to the liver, leading to worse outcomes. 

January 5 2021

Research Led by Drs. Cierpicki and Grembecka Published in "Blood"

A new study led by Drs. Jolanta Grembecka and Tomasz Cierpicki of the Department of Pathology was just published in Blood's American Society of Hematology. The research focuses on combinatorial treatment with menin and FLT3 and how inhibitors induce complete remission in acute myeloid leukemia (AML) with activating FLT3 mutations [...]

December 2 2020

Global Virtual Cancer Conference: Dr. Jeffrey Myers

Introducing the 2020 Global Virtual Cancer Conference. Join us for the segment entitled "Prevention, Diagnosis and Me" to hear from the Department of Pathology's own Dr. Jeffrey Myers, who will discuss his experiences working in the cancer community [...]

November 11 2020

Scientists Develop First Drug-Like Compounds to Inhibit Elusive Cancer-Linked Enzymes

Structural biology techniques helped researchers target the nuclear receptor-binding SET domain family, whose malfunction is associated with several types of cancer.

September 2 2020

Dr. Udager Appears on '3Ps of Cancer' Podcast

Dr. Aaron Udager recently appeared on Michigan Medicine's 3P's of Cancer: Prevention, Preparedness, Progress podcast

July 14 2020

Research Regarding Microcystic Adnexal Carcinomas Published

The research was just published in Modern Pathology and highlights the importance of next-generation sequencing within oncogenic roles for P53 and JAK/STAT signaling in microcystic adnexal carcinomas.

June 11 2020

Study from Kleer and Nesvizhskii Labs Reveals the Proteomic Landscape of Metaplastic Breast Carcinomas

Along with co-investigators, Sabra Djomehri, a graduate student in Celina Kleer's Laboratory, has discovered the proteomic landscape of metaplastic carcinomas, the most aggressive type of triple negative breast cancer. The study, published in [...]

May 1 2020
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Diagnostic Biomarkers Uncovered for Rare Kidney Cancer

Researchers have uncovered the gene signature for ChRCC.

April 21 2020
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Anti-Leukemia Compound Induces Complete Remission in Mouse Models

A Phase I clinical trial, using a structurally related analog of the compound, is currently enrolling patients.

February 3 2020

Cervical Health Awareness Month

January is Cervical Health Awareness Month. While cervical health is important twelve months of the year, it’s a great time to schedule necessary appointments and screenings. According to Dr. Richard Lieberman, with regular health screenings and the use of pap-smear testing, death rates from cervical cancer have dropped 90% since 1943. [...]

January 24 2020
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A Simple Twist of Cell Fate

U-M researchers are shedding new light with exciting implications for research and health.

January 15 2020

PCR-based TERT Promoter Assays Aid in Bladder Cancer Diagnosis

Our department's clinical resident Alex Taylor, MD, joined postdoctoral fellow Rahul Mannon, PhD, and other researchers from the Department of Pathology and the Michigan Center for Translational Pathology, who found that patients with a long-standing history of prostate cancer and other prostatic issues can find difficulty [...]

October 30 2019
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A Fundamental Passion

Bryan Betz, PhD, was inspired by his late wife, Sharon, to pursue a career in clinical diagnostics.

October 18 2019
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Cancer Patients Want to Pull Back the Curtain on Pathology

Speaking directly with a pathologist could help patients better understand their diagnosis and feel empowered, a survey of patient sentiment finds.

October 10 2019

September is Prostate Cancer Awareness Month

Every year in the United States, nearly 3 million men hear the words, “You have prostate cancer.” That is 1 in 9 men each year.  The word “cancer” triggers an immediate response in most people…fear, worry about family, denial, and often an increased awareness of one’s mortality. [...]

September 17 2019
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Making Sense Out of Tragedy

A gift from the Silver Family Foundation is funding research at Michigan Medicine.

September 17 2019

New Tool Helps Identify Patients at Risk for Hereditary Cancers

Lynn McCain and Drs. David Keren and Lee Schroeder are part of a multidisciplinary team at Michigan Medicine and Rogel Cancer Center who have developed an online tool to help identify those at risk for familial cancers. InheRET, which has already [...]

July 3 2019