News Archive

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Researchers Develop First-in-Class Inhibitors Against Key Leukemia Protein

May 17, 2021 / Cancer

A research effort by Drs. Jolanta Grembecka and Tomasz Cierpicki was just published in Nature Communications. Learn more about the protein made by the ASH1L gene, which plays a key role in the development of acute leukemia, along with other diseases [...]

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Two Proteins Critical for Kidney Function

March 24, 2021 / Faculty

Research by Drs. Ann Laszczyk and the Department of Pathology's Dr. Gregory Dressler was just published in the Journal of the American Society of Nephrology. The study focuses on PAX2 proteins and their effects on kidney function and development.

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Study Explains Why Patients with Cancer Spread to the Liver Have Worse Outcomes

January 5, 2021 / Cancer

A new study by the University of Michigan's Rogel Cancer Center analyzed patients with cancer and the factors that cause the cancer to spread to the liver, leading to worse outcomes. 

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Prostate Cancer Regulator Plays Role in COVID-19, Providing a Promising Treatment Lead

December 22, 2020 / Cancer Research

Clinical trials underway are testing whether drugs that target the androgen receptor – successful in controlling prostate cancer – could also work against the coronavirus. wo proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, MD, PhD. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers [...]

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Scientists Develop First Drug-Like Compounds to Inhibit Elusive Cancer-Linked Enzymes

September 2, 2020 / Rogel Cancer Center

Structural biology techniques helped researchers target the nuclear receptor-binding SET domain family, whose malfunction is associated with several types of cancer.

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Diagnostic Biomarkers Uncovered for Rare Kidney Cancer

April 21, 2020 / Experimental Pathology

Researchers have uncovered the gene signature for ChRCC.

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Anti-Leukemia Compound Induces Complete Remission in Mouse Models

February 3, 2020 / Experimental Pathology

A Phase I clinical trial, using a structurally related analog of the compound, is currently enrolling patients.

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A Simple Twist of Cell Fate

January 15, 2020 / Experimental Pathology

U-M researchers are shedding new light with exciting implications for research and health.

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Cancer Patients Want to Pull Back the Curtain on Pathology

October 10, 2019 / Michigan Health Blog

Speaking directly with a pathologist could help patients better understand their diagnosis and feel empowered, a survey of patient sentiment finds.

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Improving Trauma Survival Hinges on the Body's Own First Responders

March 19, 2018 / Blog

Recent discoveries about how the immune system reacts to injury — and the dire consequences
if that response spirals out of control — could help improve trauma care

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Expanding Diagnostic Services in Ghana Through Ride-Sharing

March 6, 2018 / Informatics

Some taxis in the northern part of the country will soon have new passengers: pathology samples en route to labs for testing

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Teen Meets the Heart that Almost Killed Him

March 1, 2018 / Patient And Families

A young patient with a fatal heart condition gets the chance to see his former organ up close

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How Defeating THOR Could Bring a Hammer Down on Cancer

December 14, 2017 / Blog

Newly identified RNA protein, "THOR", plays role in cancer development and could lead to new treatment.

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Why We Need You to Donate Blood Now

February 8, 2017 / Michigan Health Blog

Blood donations are used in a host of ways and often needed without warning

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