A research effort by Drs. Jolanta Grembecka and Tomasz Cierpicki was just published in Nature Communications. Learn more about the protein made by the ASH1L gene, which plays a key role in the development of acute leukemia, along with other diseases [...]
Research by Drs. Ann Laszczyk and the Department of Pathology's Dr. Gregory Dressler was just published in the Journal of the American Society of Nephrology. The study focuses on PAX2 proteins and their effects on kidney function and development.
A new study by the University of Michigan's Rogel Cancer Center analyzed patients with cancer and the factors that cause the cancer to spread to the liver, leading to worse outcomes.
Clinical trials underway are testing whether drugs that target the androgen receptor – successful in controlling prostate cancer – could also work against the coronavirus. wo proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, MD, PhD. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers [...]
Structural biology techniques helped researchers target the nuclear receptor-binding SET domain family, whose malfunction is associated with several types of cancer.
A Phase I clinical trial, using a structurally related analog of the compound, is currently enrolling patients.
Speaking directly with a pathologist could help patients better understand their diagnosis and feel empowered, a survey of patient sentiment finds.
Recent discoveries about how the immune system reacts to injury — and the dire consequences
if that response spirals out of control — could help improve trauma care
Some taxis in the northern part of the country will soon have new passengers: pathology samples en route to labs for testing