6 TRANSFUSION PROCEDURES
The transfusion procedures described in this section have been approved for use in the University of Michigan Hospitals and Health Centers.
Patient care units may have specific patient care needs that require alterations in these policies and procedures.
Alternative Procedures
Alternative procedures must be approved by the Transfusion Committee of the University of Michigan Hospitals and Health Centers and must be available to patient care personnel.
Training and Competency Assessment
Personnel who participate in the administration of blood components must be trained on hire and annually in transfusion procedures and in recognition and management of adverse reactions.
Bedside identification is required prior to the start of a transfusion.
Blood Product Administration Module (BPAM)
When barcode scanning is utilized in MiChart BPAM to verify the match between the blood product and the intended patient, the computer acts as the 2nd check for the identification verification. Documentation of the transfusion should be fully recorded in MiChart
The following barcodes must be scanned:
Manual Patient and Blood Product Verification
When MiChart BPAM is not used, the bedside identification is to be performed by qualified individuals such as a privileged provider and registered nurse, two registered nurses, or by a registered nurse and a licensed practical nurse.
Registered Nurses (RNs) and Licensed Practical Nurses (LPNs) must complete the Blood Transfusion Course and pass the quiz offered with this education. LPNs must successfully complete the state-approved pharmacology course. LPNs having met this criterion can then check blood products and monitor the recipient of the product after the first 15 minutes of the transfusion. The high risk of transfusions reactions during the first 15 minutes necessitate that an RN monitors the recipient of the product to provide any necessary intervention.
Non-physician transfusionists and anyone who assists in double checking the units (i.e. physician assistants, perfusion technicians, anesthesia allied health technicians, and emergency department technicians) must complete the "Blood Transfusion Policies" course and examination.
Equipment and Supplies
Intravenous Solutions
Component Infusion Sets
Component and Platelet Administration sets with shorter tubing are available from the Materiel Service Center (MSC) section of Materiel Services.
Leukocyte-Reduction Filters
Pressure Infusion Devices
Follow the filter, port or catheter manufacturer’s instructions regarding the use of pressure infusion devices. The flow through some blood filters may be compromised and some catheters may cause catheter wall rupture if a pressure infusion device is used.
Blood Warmers
Blood warmers are available from the operating rooms.
Blood warmers may be used as long as the device has a temperature alarm and visible temperature monitor. Blood warming devices are most appropriate for massive and rapid blood replacement, such as exchange transfusion of the newborn.
Patient Instructions and Preparation
Blood Bank personnel will notify patient unit personnel by telephone when ordered blood is ready for transfusion.
Informed Consent Updated 12/16/13
Refusal of Blood Transfusion
Post Transfusion Instructions to the Patient
Release and Transport of Blood Components
To reduce the potential for waste of the component, do the following before requesting that a blood component be issued from the Blood Bank:
1 |
Verify the physician's order for the product, volume and transfusion rate Note: Orders for blood components shall follow the policies for patient care orders and verbal orders for inpatient and out patients ( UMHHC Policy 62-10-003 Patient Care Orders, UMHHC Policy 62-10-006 Inpatient Verbal Orders and UMHHC Policy 62-10-007 Verbal Orders - Ambulatory Care). |
2. |
Administer any pretransfusion medication. |
3. |
Record the patient's vital signs. |
4. |
Initiate or verify patency of an intravenous line. |
Requesting blood components to be sent to the patient location
Electronic or verbal requests must contain the following information in order for blood to be issued:
1. |
Patient's full name and Medical Record Number. |
2. |
Blood component to be issued. |
3. |
Number of blood components to be issued. |
4. |
Patient location (tube station number if applicable). |
5. |
Verify a read-back of the request if verbally requesting blood to be issued. |
(4/28/15)
Packaging of Blood Components
Blood Bank will package the blood components based on the intended transport method. Multiple products may be issued to areas with blood refrigerators. Multiple products may be issued to areas without blood refrigerators when packaged appropriately for the component issued.
Pneumatic tube system |
Ziploc plastic bag (silver padded envelope for Mott OR) |
Unit staff at BB window |
Ziploc plastic bag or padded envelope Cooler/Massive Transfusion Pack/Trauma Pack when indicated |
Phlebotomy staff (during tube system down or large number of products) |
Ziploc plastic bag or padded envelope |
Courier delivery to off-site infusion locations |
Blood Box (packed appropriately for component) |
Picking up blood at the Blood Bank window
Transporting Blood Components
Receipt of Blood Components
The person receiving the blood being transported or opening the tube at the receiving location must immediately upon receipt
Step |
Action |
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1 |
Verify
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2 |
The person receiving the blood component should:
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3 |
Return the signed and dated Blood Delivery Form to the Blood Bank using hospital mail |
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4 |
Verify that red blood cells and plasma components were received within 30 minutes of the dispensed time stamp on the form. If Then |
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If more than 30 minutes have elapsed since the time stamp on the Blood Delivery Form |
the Red Blood Cells or plasma may be used for immediate transfusion that will be completed within 4 hours of the time stamp, transfuse the component. |
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Do not store Red Blood Cells and plasma that has been out of refrigeration for more than 30 minutes in patient care unit Blood Refrigerators. |
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If the blood component is not needed for immediate transfusion, return the Red Blood Cells or plasma to the blood bank for proper disposal. |
Special Labels
IMMEDIATELY PRIOR TO BLOOD TRANSFUSION
Pretransfusion Vital Sign Documentation
If a patient is febrile, consideration should be given to postponement of blood transfusion, since the fever may mask the development of a febrile reaction to the blood component itself.
Two qualified individuals must
These steps must never be bypassed.
1 |
Ask the patient to state his or her name. Verify patient and component identification information. |
2 |
Verify the blood type, donor number, component name |
3 |
Verify compatibility: a compatibility chart is on the back inside cover of this booklet. |
4. |
Verify the product is not outdated |
5. |
Sign the Transfusion Record Form before blood transfusion is initiated. |
6. |
The person who hangs the blood must record the date and time the transfusion was started |
7. |
Record the date, time, component and unit number on the appropriate sheet on the patient's chart. Refer to unit policy and procedures. |
DO NOT START the transfusion if there is any discrepancy.
Contact the Blood Bank.
Initiating the Transfusion
Flow Rates
Initial Flow Rate |
Slowly at no more 2 mL/minute to allow for recognition of an acute adverse reaction. Proportionately smaller volume for pediatric patients. |
Standard Flow Rate - Adults |
If no reaction occurs in the first 15 minutes, the rate may be increased to 4 mL/minute. |
Pediatrics |
10-20 mL/kg unless the patient can tolerate only gradual expansion of the intravascular volume. The usual infusion time is 1.5-2hrs. |
Usual Infusion time |
Red Blood Cells: two hours unless the patient can tolerate only gradual expansion of the intravascular volume Platelets, plasma and cryoprecipitate: The transfusion may be administered as rapidly as the patient can tolerate, usually 30 minutes.
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Maximum Infusion Time |
Infusion time should not exceed 4 hours for any component. |
If rate slows appreciably |
investigate immediately Consider measures that may enhance blood flow
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During the Transfusion Document
What |
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When |
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Outpatient Post Transfusion Vital Signs |
For outpatient transfusions, the vital signs may be taken at 30 minutes post transfusion. |
See Chapter 7 for details concerning the signs and symptoms of a transfusion reaction.
If the patient has a preexisting fever
The need for transfusion must be balanced with the risk of transfusion. Contact the patient’s physician to determine if pretransfusion medications should be administered.
If a patient is being transported with blood hanging
Patients should not be transported with blood components infusing unless accompanied by a clinician who can monitor and respond to a potential reaction. Additionally, the receiving clinic/area must have a clinician who can manage a patient while they are receiving blood components.
Medications
Units entered and not transfused
If a unit of blood or a blood component has been entered for any reason by personnel not working in the Blood Bank, and the unit has not been transfused
If Components Are No Longer Needed
To avoid unnecessary waste of blood resources, notify the Blood Bank staff immediately if components are no longer needed for a patient, as the component may be suitable for transfusion to another patient. Return any unneeded units to the blood bank.
At the Termination of an Uncomplicated Transfusion
After the completion of each uncomplicated transfusion, the responsible physician or nurse should verify that the "Transfusers Must Complete" section of the Transfusion Record Form
is complete, including
Discontinue the isotonic saline solution used to initiate the transfusion after the completion of the transfusion unless specifically ordered.
Document the patient's response to the transfusion in the patient's medical record.
If a Transfusion Reaction is Suspected
Disposal of Blood Bags If No Reaction is Suspected
Discard empty blood bags with attached blood infusion sets on the patient unit in a biohazard waste container such as a red bag.
Transfusion Record Form Distribution
Following completion of the form, the white copy of this form should be retained in the patient unit for attachment to the patient's chart; the pink copy of the form must be returned to the Blood Bank in hospital mail.
SPECIAL INSTRUCTIONS FOR HEMATOPOIETIC PROGENITOR CELL (HPC) INFUSION
Autologous stem cells are the patient's own stem cells that are harvested from the marrow or peripheral blood and then cryopreserved.
Allogeneic Bone Marrow is fresh stem cells taken from a donor's bone marrow. Allogeneic stem cells are taken from the peripheral blood by apheresis. After collection these cells may be cryopreserved.
Physician Orders |
There must be a written order from a hematology/oncology staff physician for the infusion. |
Transfusionist Qualifications |
HPC must be administered by a physician or an experienced Bone Marrow Transplant RN or Physician Assistant under the direct supervision of a physician. A physician or Physician Assistant must be present on the unit during autologous HPC re-infusion with emergency equipment available at the bedside. |
Maximum time from thaw to infusion |
HPC products must be infused within 15 minutes of thawing. They cannot be stored since the cryoprotective agent DMSO is toxic to cells at 4 C. |
Storage temperature of stems cells that are not frozen |
Room temperature or if the infusion cannot be initiated immediately after processing is complete, the marrow may be stored in the Blood Bank at 4 C for no more than 24 hours |
Compatible IV solution |
Isotonic (0.9%) saline is the only solution compatible with stem cell products |
Irradiation |
Stem cell products are not irradiated. |
Infusion equipment |
Administer through a central venous catheter. Do not administer through a blood filter. Updated 1/10/14 |
Documentation of Vital Signs |
Vital signs must be documented after the first 15 minutes of the infusion, at half hour intervals during an allogeneic infusion, every 15 minutes during an autologous infusion and then every 30 minutes for one-hour post infusion. |
Adverse Reactions |
Adverse reactions associated with any blood component transfusion apply to HPC. . In addition, reactions due to the cryopreservative DMSO and the lack of an infusion filter may also occur. Monitor the patient closely for symptoms such as hypertension, dyspnea, pulmonary edema, chest pain, bronchospasm, abdominal cramping, hypoxia, headache, nausea, vomiting, fever, chills, hypertension, hemoglobinuria and urticaria. |
If a reaction occurs |
If symptoms develop, slow the infusion. Notify the patient's physician and the Blood Bank physician on-call. |
ABO-incompatible stem cell products |
Patients receiving a major ABO-incompatible HPC product will likely develop an acute hemolytic reaction depending on the volume of ABO incompatible cells infused. See chapter 7. |
Red discoloration of the urine |
A red discoloration of the urine commonly occurs up to 24 hours after the infusion of cryopreserved HPC as a result of the dye in the processing media. This occurrence does not need to be reported as a transfusion reaction. |