UdagerThe University of Michigan SPORE in Prostate Cancer has awarded Aaron Udager, MD, PhD, with a two-year Prostate SPORE Career Enhancement Program (CEP) grant of $60,00 per year. The Department of Pathology will contribute matching funds of another $10,000 per year, bringing the total to $70,000 per year.
The U-M Prostate SPORE was established in 1995 to tap physical and intellectual resources from the university community and provide them with resources in order to decrease patient morbidity and mortality due to prostate cancer. Significant translational discoveries have been made through the program, including the identification of recurrent ETS gene fusions in prostate cancer and germline mutations in the HOXB13 gene that increase prostate cancer risk.
Dr. Udager will use his award to fund his project Integrative targeted next-generation DNA and RNA sequencing of multiclonal prostate cancer index nodules: implications for molecular biomarker assessment. The project seeks to use cutting-edge multi-region next-generation sequencing (NGS) technology to determine the impact of multiclonality on prostate cancer molecular biomarker assessment. Multiclonal tumors are tumors that are actually comprised of two tumors with distinct molecular profiles (both ERG-positive and ERG-negative) which have grown together or "collided" in the prostate. These tumors affect a subset of prostate cancer patients (less than 15%) and complicate interpretation of new molecular assays that can determine clinical management of the disease. This project aims to better understand these tumors and could lead to more individualized treatment for these patients with improved outcomes. Dr. Scott Tomlins will collaborate on the project and Dr. Arul Chinnaiyan will serve as Dr. Udager's mentor for the project.
This project was made possible in part by prior work by Dr. Tomlins and Mr. Javed Siddiqui, with funding through a Department of Defense Prostate Cancer Research Program Idea Development Award.
Dr. Udager will meet quarterly with the Prostate SPORE CEP directors, Drs. Didi Robins and Ganesh Palapattu, in order to establish project milestones.
Learn more about the work of the University of Michigan SPORE in Prostate Cancer by visiting the Translational Research Program on the National Cancer Institute's website.
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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Dr. Sriram Venneti, MD, PhD and Postdoctoral Fellow, Chan Chung, PhD investigate pediatric brain cancer. See Article 2017Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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Director of the Neuropathology Fellowship, Dr. Sandra Camelo-Piragua serves on the Patient and Family Advisory Council. 2018Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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Residents Ashley Bradt (left) and William Perry work at a multi-headed scope in our new facility. 2019Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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Dr. Kristine Konopka (right) instructing residents while using a multi-headed microscope. 2020Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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Patient specimens poised for COVID-19 PCR testing. 2021Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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Dr. Pantanowitz demonstrates using machine learning in analyzing slides. 2022Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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(Left to Right) Drs. Angela Wu, Laura Lamps, and Maria Westerhoff. 2023Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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Illustration representing the various machines and processing used within our labs. 2024Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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MLabs, established in 1985, functions as a portal to provide pathologists, hospitals. and other reference laboratories access to the faculty, staff and laboratories of the University of Michigan Health System’s Department of Pathology. MLabs is a recognized leader for advanced molecular diagnostic testing, helpful consultants and exceptional customer service.