Congratulations to Dr. Celina G. Kleer for receiving the 2019 American Association for Cancer Research (AACR) Outstanding Investigator Award for Breast Cancer Research from the San Antonio Breast Cancer Symposium (SABCS) and the AACR, supported by the Breast Cancer Research Foundation (BCRF). This award is given annually at the American Society for Investigative Pathology meeting for scientists who have made seminal contributions to breast cancer research.
Dr. Kleer received her medical degree from the University of Buenos Aires School of Medicine in Buenos Aires, Argentina in 1993. Her passion for disease and pathological changes began as she was a histology teaching assistant, and worked in the laboratory of Dr. Amanda Pellegrino de Iraldi, one of the most renowned scientists in Argentina, where she learned to perform electron microscopy. Upon coming to the U.S., Dr. Kleer began her residency in Anatomic and Clinical Pathology at the Mayo Clinic in Rochester, Minnesota, and continued her residency and surgical pathology fellowship training at the University of Michigan, specializing in breast pathology with Dr. Harold A. Oberman, a pioneer in the field, and an advocate for women in medicine. In 1999, she joined the faculty at the University of Michigan Department of Pathology and was extremely fortunate to work with Dr. Sofia D. Merajver, a clinician scientist who inspired her lifetime dedication to breast cancer research. In November 2007, Dr. Kleer became the first Harold A. Oberman Collegiate Professor of Pathology at age 36, and reached the rank of full professor with tenure in 2011.
In conjunction with her clinical work, Dr. Kleer is the principal investigator of a federally funded research laboratory at the University of Michigan Rogel Cancer Center working to understand mechanisms of breast cancer invasion and metastasis, and to develop useful breast tissue-based biomarkers. Her work bridges basic science and clinical application, with 150 peer reviewed papers. Of particular interest are non-canonical functions of the Polycomb group protein EZH2 in breast cancer metastasis, in particular using novel mouse models and molecular biology approaches. A main focus of the lab has been elucidating the underlying mechanism of metaplastic breast carcinomas, the most aggressive form of triple negative breast cancer.
Dr. Kleer is a dedicated mentor to medical students, graduate students, and physician residents both in the laboratory and in surgical pathology. She has enjoyed mentoring high school and undergraduate students in the lab and instilling the enthusiasm for medicine and science that has fueled her life. In particular, she has been an advocate for women and minority trainees many of whom have been persons of color, or from families where the trainee may have been the first one to attend college. Because of her dedication to education, she received the 2018 Distinguished Clinical and Translational Research Mentor Award by the University of Michigan Institute for Clinical and Health Research, which recognizes mentors across disciplinary boundaries in pursuit of science, from across the University of Michigan.
She is a permanent member of the NIH/NCI Cancer Prevention Study Section and participates in scientific Editorial Boards including serving as Associate Editor of JCI Insight and Breast Cancer Research. She has served in the Editorial Board of AJP for several years. Dr. Kleer is an elected member of the American Society for Clinical Investigation (ASCI).
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This story originally appeared on the ASIP Pathways website on 5/6/2020. The full publication is accessible here.
ON THE COVER
Breast team reviewing a patient's slide. (From left to right) Ghassan Allo, Fellow; Laura Walters, Clinical Lecturer; Celina Kleer, Professor. See Article 2014Department Chair |
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INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
Autopsy Technician draws blood while working in the Wayne County morgue. See Article 2016Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
Dr. Sriram Venneti, MD, PhD and Postdoctoral Fellow, Chan Chung, PhD investigate pediatric brain cancer. See Article 2017Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
Director of the Neuropathology Fellowship, Dr. Sandra Camelo-Piragua serves on the Patient and Family Advisory Council. 2018Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
Residents Ashley Bradt (left) and William Perry work at a multi-headed scope in our new facility. 2019Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
Dr. Kristine Konopka (right) instructing residents while using a multi-headed microscope. 2020Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
Patient specimens poised for COVID-19 PCR testing. 2021Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
Dr. Pantanowitz demonstrates using machine learning in analyzing slides. 2022Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
(Left to Right) Drs. Angela Wu, Laura Lamps, and Maria Westerhoff. 2023Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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ON THE COVER
Illustration representing the various machines and processing used within our labs. 2024Department Chair |
newsletter
INSIDE PATHOLOGYAbout Our NewsletterInside Pathology is an newsletter published by the Chairman's Office to bring news and updates from inside the department's research and to become familiar with those leading it. It is our hope that those who read it will enjoy hearing about those new and familiar, and perhaps help in furthering our research. CONTENTS
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MLabs, established in 1985, functions as a portal to provide pathologists, hospitals. and other reference laboratories access to the faculty, staff and laboratories of the University of Michigan Health System’s Department of Pathology. MLabs is a recognized leader for advanced molecular diagnostic testing, helpful consultants and exceptional customer service.