10th Annual Protein Folding Diseases Initiative Symposium

By Catherine Niemiec | August 17 2023

September 21, 2023

If you have any questions related to this event, please contact Cathy Niemiec at cniemiec@umich.edu.

Register Today


Symposium Program

Morning

8:25am

Opening Remarks
by Andy Lieberman, M.D., Ph.D., Gerald D. Abrams Collegiate Professor, Director of Neuropathology, and Co-Director of the Protein Folding Diseases Initiative

8:30am

Shu-ou Shan, PhD
Altair Professor of Chemistry; Executive Officer for Biochemistry and Molecular Biophysics, California Institute of Technology, “Molecular Machines in Protein Biogenesis:  On the Ribosome and Beyond”

9:15am

Ming Li, PhD
Associate Professor, Molecular, Cellular and Developmental Biology “ER-Associated Degradation in Cystinosis Pathogenesis and the Prospects of Precision Medicine”

9:35am

Bing Ye, PhD
Professor, Life Sciences Institute, Cellular and Developmental Biology, “Elevated Levels of Down Syndrome Cell Adhesion Molecule Cause Presynaptic Overgrowth in Animal Models of Down Syndrome”

9:55am

Yanzhuang Wang, PhD
Professor, Molecular, Cellular and Developmental Biology, “GRASP55 Regulates Unconventional Secretion and Aggregation of Neurodegenerative Proteins”

10:15am

Peter Arvan, MD, PhD
William K. and Delores S. Brehm Professor of Diabetes Research and Co-Director of the Protein Folding Diseases Initiative, "Proinsulin biosynthesis

10:35am

BREAK

10:45am

Stephanie Moon, PhD
Assistant Professor, Human Genetics, “Regulation of RNA in Stress and Disease”

11:05am

Ryan Baldridge, PhD 
Assistant Professor, Biological Chemistry, “Targeted Protein Degradation from the ER”

11:25am

Sethu Pitchiaya, PhD
Assistant Professor, Urology and Pathology, “Biomolecular Condensates Modulate Transcriptional Responses to Proteotoxic Stress”

11:45am

Lisa Sharkey, PhD
Assistant Professor, Neurology, “Retrotransposon Regulation of Ubiquilin-2 Biology; Implications for ALS Research”

Afternoon

12:05pm

Lunch & Poster Review
Seminar Rooms A, B, C, and Upper Atrium

Young Investigator Session

2:30pm

Erin Kropp, MD
House Officer VI, “Identifying Small Molecule Modulators of Endoplasmic Reticulum Associated Degradation in Multiple Myeloma”

2:50pm

Shannon Lacy, PhD Candidate
Cellular & Molecular Biology, “Impact of FICD-Mediated Protein AMPylation on Cardiac Function”

3:10pm

Maroof Alam, PhD
Research Fellow, Metabolism, Endo & Diabetes, “Alternate-Day Fasting in Animals Predisposed to Proinsulin Misfolding Reverses Diet-Induced Diabetes”

3:30pm

Ryan Neff
DSCAM’s Role in Dendritic Phenotypes Associated with Down Syndrome”

3:50pm

Randy Hampton, PhD
Professor, Cell and Developmental Biology, University of California, San Diego “Mallostery:  Employing Protein Quality Control for Metabolic Regulation”

4:30pm

Closing Remarks & Awards
by Peter Arvan, M.D., Ph.D., William K. and Delores S. Brehm Professor of Diabetes Research and Co-Director of the Protein Folding Diseases Initiative