Associate Professor
Email: jrual@umich.edu
Phone: 734-764-6975
Dr. Jean-Francois (Jeff) Rual received a B.S. in Biochemistry and Molecular Biology from the University of Nice Sophia-Antipolis (Nice, France) in 1999 and a M.S. in Microbiology and Virology from the Pasteur Institute (Paris, France) and the University of Nice Sophia-Antipolis in 2000. He then went on to receive a M.S. in Bioinformatics from the University of Notre Dame de la Paix (Namur, Belgium) in 2001. He completed his graduate research studies in the Department of Genetics at Harvard Medical School (Boston, MA) in the laboratory of Prof. Marc Vidal and received his Ph.D. from the University of Notre Dame de la Paix in Molecular Biology in 2005. After two years as Project Leader at the Center for Cancer Systems Biology (CCSB) at Harvard Medical School under the direction of Prof. Marc Vidal (2005-2007), Dr. Rual joined the laboratory of Prof. Spyros Artavanis-Tsakonas in the Department of Cell Biology at Harvard Medical School (2007-2011). His post-doctoral training in the Artavanis-Tsakonas Lab was supported by a José Carreras International Leukemia Foundation Fellowship Award. In July 2011, Dr. Rual joined the faculty of the Department of Pathology at the University of Michigan as an Assistant Professor and is an American Society of Hematology (ASH) Scholar (2013-2015). Dr. Rual was promoted Associate Professor in the Department of Pathology at the University of Michigan in 2020.
Caryn Crane
Administrative Assistant
Email: ccaryn@med.umich.edu
Phone: 734-764-6683
Fax: 734-763-8764
Caryn joined the Rual Lab as Administrative Assistant in August 2016.
Research Specialist
Email: honglaiz@med.umich.edu
Phone: 734-764-8736
Danfeng Luo
Claire Peabody
M-Cubed Scholar
Claire joined the Rual lab in June 2017 as part of the M-Cubed Scholars Program. She worked on the in vivo characterization of modulators of Hedgehog signaling in mouse models of brain tumorigenesis. Since 2021, she is enrolled as an MD student at the SUNY Downstate College of Medicine in Brooklyn, NY.
Research Fellow
Dr. Sung-Soo Park joined the Rual Lab as a Research Fellow in November 2011. He investigated the molecular network in which Notch signaling pathway proteins are involved using a MS-based approaches. Sung-Soo now works in the biotech company Helixmith in Seoul, South Korea.
Ester Calvo Fernandez
St. Baldrick’s Staff Giving Campaign Summer Fellow
Ester worked in the Rual lab from January 2018 to June 2019 as a Visiting Research Scholar from the University of Barcelona, Spain. She obtained the St. Baldrick’s Staff Giving Campaign Summer Fellowship from the St. Baldrick's Foundation to pursue her work in the Rual lab for the in vivo characterization of modulators of Notch signaling in mouse models of brain tumorigenesis. Ester joined the Columbia University Medical Center in June 2019 as a PhD Candidate in the Pathobiology and Mechanisms of Disease PhD Program.
Sarah Cooke
M-Cubed Scholar
Sarah worked in the Rual lab from June 2017 to August 2017 as part of the M-Cubed Scholars Program. She worked on the in vitro characterization of newly identified RBPJ interactors for their ability to modulate Notch signaling.
Research Fellow
Jessica Erickson
Undergraduate Student
Jessica worked in the Rual lab from October 2016 to May 2017 as part of the Undergraduate Research Opportunity Program (UROP). She worked on the in vivo characterization of modulators of Hedgehog signaling in mouse models of brain tumorigenesis.
Undergraduate Student
Alaina worked in the Rual lab from September 2015 to May 2016 as part of the Undergraduate Research Opportunity Program (UROP). She worked on the molecular characterization of modulators of Hedgehog signaling.
Undergraduate Student
Justin worked in the Rual lab from September 2015 to November 2017 as part of the Undergraduate Research Opportunity Program (UROP). He worked on the in vivo characterization of modulators of Notch signaling in mouse models of brain tumorigenesis. Justin joined the class of 2022 at the Case Western Reserve University School of Medicine.
Community College Summer Research Fellow
Arinze worked in the Rual lab from June 2014 to April 2015 as a part of the Community College Summer Research Fellowship Program .
Cancer Research Summer Intership Intern
Ryan worked in the Rual lab from June 2014 to April 2015 as a part of the Cancer Research Summer Intership Program (CaRSIP) .
Undergraduate Student
Kimberly joined the Rual lab in October 2011 and worked in the Rual lab for 3 years. She worked on the characterization of Notch -related protein-protein interactions using the Y2H system. She is now a Graduate Student in the Doctor of Pharmacy program at the University of Illinois , Chicago, IL.
Research Assistant
Rita joined the Rual Lab from October 2012 to June 2014 as a Research Assistant.
Graduate Student
Eléna worked in the Rual lab from July 2012 to February 2013 as a visiting Graduate Student from ENSTBB , at the University of Bordeaux, France. During her stay in the lab, Eléna worked on the characterization of Notch -related protein-protein interactions discovered using the Y2H system. Eléna is now working as a Market Researcher at Prescient Life Sciences , a pharmaceutical consultancy based in London, UK.
UROP Undergraduate Student
As part of the Undergraduate Research Opportunity Program (UROP), Anji worked in the Rual lab from September 2012 to March 2013. She works on the characterization of the Notch molecular network using an AP-MS approach.
UROP Undergraduate Student
Mahnoor joined the Rual lab from October 2011 to April 2012 as part of the Undergraduate Research Opportunity Program (UROP) . She worked on the characterization of HOXA9-related protein-protein interactions using the Y2H system.